Senior/Executive Director, Reverse Translation, Oncology Translational Research Job at Johnson & Johnson, Spring House, PA

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  • Johnson & Johnson
  • Spring House, PA

Job Description

Johnson & Johnson seeks a Senior/Executive Director to lead reverse-translation research in oncology, driving mechanistic studies across the therapeutic area and supporting active disease programs. The role combines independent investigation of cross-cutting biology questions with laboratory-based support for clinical translation, requiring leadership of consolidated bench-science teams.

Responsibilities

  • Lead independent mechanistic studies on high-priority cross-therapeutic-area questions with dedicated resources and mandate
  • Prioritize and pursue disease-focused, mechanism-focused, and legacy program questions; develop findings into next-generation hypotheses and combination strategies
  • Consolidate disease-area program scientists into single laboratory team; build and manage omics, functional biology, and preclinical model platforms
  • Address active scientific questions from disease-area leads on mechanism, resistance, and combinations, returning actionable answers on defined timelines
  • Serve on Core SLT for Translational Research, linking reverse translation to Discovery and Medical Affairs/Commercial to inform lifecycle and portfolio priorities

Requirements

  • PhD, MD, or MD/PhD in cancer biology, molecular biology, immunology, pharmacology, or related discipline
  • 10+ years (Senior Director) or 12+ years (Executive Director) in oncology discovery or translational research with hands-on lab leadership
  • Broad mechanism-of-action and mechanism-of-resistance expertise with demonstrated ability to translate clinical observations into testable hypotheses
  • Experience building and leading wet-lab teams, operating omics and functional-characterization platforms
  • Effective collaboration at the Discovery–Translational Research interface across multiple disease areas and matrix structures
  • Strong publication record with first and last author contributions

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